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PEG-MGF (Mechano-Wachstumsfaktor)
💧 Bacteriostatic Water (Included)
€55,00
One-time
- Promotes muscle cell proliferation and growth
- Enhanced recovery from mechanical tissue damage
- Extended half-life due to PEGylation
- Stimulates satellite cell activation
- Supports connective tissue repair
- Injection site irritation (mild, transient)
- Localized swelling (rare)
- Hypoglycemia (rare, dose-dependent)
- Fatigue (occasionally reported)
For research use only. Not for human consumption. Data from published preclinical and clinical studies.
Bacteriostatic Water
1 ml
Slowly drip along the vial wall. Do not shake — gently swirl.
Frequency
2–3× per week
Subcutaneous/intramuscular injection. Post-workout.
Concentration
2 mg/ml
2 mg / 1 ml = 2 mg/ml. Every 10 units (0.1 ml) = 0.2 mg.
Titration
Not required
200 mcg per dose, 2–3× per week.
Storage:Before reconstitution, store refrigerated (2–8 °C) or frozen (-20 °C). After reconstitution, keep refrigerated and use within 28 days. Protect from direct sunlight.
PEG-MGF is a PEGylated form of Mechano Growth Factor, a splice variant of the IGF-1 gene that is naturally expressed in response to mechanical stress on muscle tissue. The addition of a polyethylene glycol (PEG) chain significantly increases the peptide's molecular stability and extends its half-life, making it particularly suitable for extended observation in controlled laboratory environments. MGF plays a critical role in muscle repair by activating satellite cells — the stem cells responsible for muscle fiber regeneration.
Mechano Growth Factor was first identified through research into the IGF-1 gene's alternative splicing patterns. Scientists discovered that mechanical loading of muscle tissue triggers the expression of a specific IGF-1 splice variant — MGF — distinct from the liver-derived IGF-1Ea isoform. The PEGylated version was developed to overcome native MGF's extremely short half-life (minutes), which limited its usefulness in research settings. By attaching a PEG chain, researchers extended the biological availability from minutes to hours, enabling more practical experimental protocols.
PEG-MGF has been studied extensively in muscle biology and regenerative medicine research:
Key Areas:
- Muscle Regeneration — PEG-MGF activates muscle satellite cells and promotes myoblast proliferation, key steps in muscle repair following damage.
- Satellite Cell Activation — Research demonstrates that MGF uniquely activates quiescent satellite cells — muscle stem cells — initiating the repair cascade.
- Bone & Cartilage — Emerging studies suggest MGF isoforms play roles in osteoblast proliferation and cartilage repair.
- Cardiac Tissue — Preclinical studies have explored MGF's cardioprotective properties, showing potential to reduce cardiomyocyte apoptosis.
PEG-MGF represents a significant advancement in growth factor research, providing a stable platform for investigating IGF-1 splice variant biology across multiple tissue types.
Yang SY, Goldspink G. Different roles of the IGF-I Ec peptide (MGF) and mature IGF-I in myoblast proliferation and differentiation. — FEBS Lett. 2002Hill M, Goldspink G. Expression and splicing of the insulin-like growth factor gene in rodent muscle is associated with muscle satellite cell activation. — J Physiol. 2003Carpenter V, et al. Mechano-growth factor reduces loss of cardiac function in acute myocardial infarction. — Heart Lung Circ. 2008
Frequently Asked Questions
Everything you want to know about PEG-MGF and our research compounds.
PEG-MGF (PEGylated Mechano Growth Factor) is a modified form of the IGF-1 splice variant known as MGF. It is naturally produced in muscle tissue in response to mechanical stress or damage. The PEG modification extends its biological half-life from minutes to hours. PEG-MGF primarily works by activating satellite cells — the muscle stem cells responsible for repair and regeneration.
While both are related to the IGF-1 gene, they are distinct peptides. IGF-1 (specifically IGF-1Ea) is primarily liver-derived and promotes general growth. MGF is a locally-produced splice variant that specifically activates satellite cells for muscle repair. PEG-MGF is the stabilized version with an extended half-life for research applications.
Every single batch undergoes independent third-party testing via HPLC (High-Performance Liquid Chromatography) and mass spectrometry — the gold standard in peptide analysis. We guarantee 99%+ purity on every vial. Certificates of Analysis are available for download directly on this page.
Orders are dispatched within 1-3 business days from our EU facility via FedEx with full tracking. EU delivery takes 1-3 days, US 2-4 days, Middle East 2-4 days. Every package is temperature-controlled and discreetly packed to maintain peptide stability.
Each vial contains exactly 2mg of lyophilized (freeze-dried) PEG-MGF peptide in powder form. Lyophilization ensures maximum stability — the powder remains potent for up to 2 years when stored properly at -20°C. After reconstitution with bacteriostatic water, refrigerate at 2-8°C and use within 4 weeks.
Three reasons: Verified purity — every batch tested with downloadable CoA. EU-manufactured — synthesized under strict pharmaceutical-grade conditions, not resold from unverified sources. Photo proof — we send you a photo of your exact order before it ships.
We accept Visa, Mastercard (select 'Pay Now' at checkout), and SEPA bank transfer for EU customers. All transactions are processed securely.
All products are sold strictly for laboratory and research purposes. They are not intended for human or animal consumption. Bionic Labs operates as a licensed chemical supplier within the EU, with full documentation, lot tracking, and third-party quality verification on every batch we produce.
Customer Reviews
5.0 — Based on 24 reviews
JW
James W. 🇬🇧✅ Verified Buyer
Stable and Consistent
Been running PEG-MGF for a muscle regeneration protocol and the extended half-life is noticeable compared to non-PEGylated variants I've used before. Bionic Labs is consistent batch to batch, packaging always professional. Highly recommend.
LM
Lars M. 🇩🇪✅ Verified Buyer
Great Product
Exactly as described. Works as expected for my satellite cell activation research. Shipping was fast too. No issues.
SK
Sophie K. 🇳🇱✅ Verified Buyer
PEG-MGF 2mg
The product is great. It arrived early, and the packaging was intact. I was extremely impressed with the quality and even more so with the customer service I have received. The PEGylation really does extend the working window compared to regular MGF in my protocols. Great product.
MR
Marco R. 🇮🇹✅ Verified Buyer
I love this!
To have this peptide available to purchase is amazing!! The shipping was quick too!
OP
Oliver P. 🇬🇧✅ Verified Buyer
Awesome! Best quality
Bionic Labs never disappoints. Best in the business for growth factor peptides.
PD
Pierre D. 🇫🇷✅ Verified Buyer
Great Quality
Great quality product, professional customer service. Muscle regeneration research has gone smoothly with this batch.
TJ
Tomas J. 🇪🇸✅ Verified Buyer
Ordering online was easy, user-friendly!
Ordering online was easy, user-friendly! Shipping was fast. Email communication from Bionic Labs was very convenient and reassuring! I really appreciate this!!
NB
Niklas B. 🇸🇪✅ Verified Buyer
Great Price and Product
Shipped quickly and received exactly what I needed for my muscle repair research. Thanks.
HV
Henrik V. 🇩🇰✅ Verified Buyer
PEG-MGF 2MG
Works great for satellite cell studies
FB
Florian B. 🇦🇹✅ Verified Buyer
Excellent Choice
So far I am very pleased with the product. Highest quality available for a PEGylated growth factor peptide.
JK
Jan K. 🇵🇱✅ Verified Buyer
Exactly what i was looking for
Got my order quick and everything was correct. Connective tissue repair research is progressing well. Will order again soon.
AT
Ana T. 🇵🇹✅ Verified Buyer
Fantastic!
Product was shipped very quickly and securely. As described!
DH
David H. 🇬🇧✅ Verified Buyer
PEG-MGF
Works great. Muscle regeneration research going well.
CC
Cristian C. 🇷🇴✅ Verified Buyer
Go to Supplier!
Go to Supplier! Best around in my experience for growth factor peptides.
MD
Matej D. 🇨🇿✅ Verified Buyer
PEG-MGF 2mg
Legit peps. Works great for muscle cell proliferation research!
ER
Erik R. 🇳🇴✅ Verified Buyer
Love the product
Love this peptide, huge help with my recovery timelines in the lab
AP
Adriaan P. 🇧🇪✅ Verified Buyer
Review
Excellent product, exactly as described on the CoA
SS
Stefan S. 🇩🇪✅ Verified Buyer
Love it!
Quality, timely delivery, consistent product batch after batch
AG
Andreas G. 🇨🇭✅ Verified Buyer
Good
Good, noticeable difference in my muscle repair research
JJ
Javier J. 🇪🇸✅ Verified Buyer
Product was as advertised
Shipping was quick and ordering was easy.
GS
Giovanni S. 🇮🇹✅ Verified Buyer
best Quality
Fast shipping, great for my satellite cell activation research
JH
Joost H. 🇳🇱✅ Verified Buyer
So far so good
So far so good, will update after a full research cycle
PEG-MGF (Mechano-Wachstumsfaktor)
💧 Bacteriostatic Water (Included)
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